Single-stranded DNA (ssDNA) pairs the stability of double-stranded DNA and the flexibility of RNA to offer the best of both worlds in today’s therapeutic nucleic acids. Kano’s fermentation-based ssDNA production technique enables gene-length circular single-stranded DNA templates: a fundamentally better building block for genomic engineering.
CRISPR alone works well to cut and remove faulty genetic material, but to fully realize the potential of therapeutic gene editing we need complementary technology to insert long stretches of DNA site specifically.
Our DNA donors complement CRISPR or any other gene editing tool used to insert synthetic genes.
We use fermentation-based DNA production: a tried-and-true method for cost effective manufacturing at scale. Additionally, we’re building a first-of-its-kind databank linking ssDNA sequence design to activity, speeding up development timelines and saving time and money for our partners.