Lack of DNA payload innovation is a fundamental industry bottleneck that limits which therapies can reach patients. Kano is committed to perfecting the genetic payload itself, eliminating the risks of working with viral vectors or toxic double-stranded DNA products. Our circular single-stranded DNA (cssDNA) offers precision editing, superior persistence, and in vivo safety. It functions as a versatile building block, working across delivery modalities and therapeutic approaches
Shape Matters: Circular ssDNA isn’t just “DNA without a second strand.” Its topology and 3D features can be engineered to influence stability, intracellular behavior, and downstream performance.
Not with Kano. We manufacture ssDNA using industrial fermentation. Traditional ssDNA is produced through chemical or enzymatic methods that don’t scale economically. Kano uses fermentation-based manufacturing, similar to biologics and plasmid DNA production, to generate circular ssDNA for reliable supply from research through GMP.
We license DNA products — and supply them — in one integrated partnership. Partners typically start with a low-friction evaluation agreement to generate data in their own system. From there, we move into a full partnership designed based on the need of your therapeutic pipeline with integrated DNA supply from discovery through GMP. One agreement. One payload platform. Full support from concept to clinic.
